Throughout 2013 I have been using Dr Passers' induction routine, starting with 4mg and increasing by 2 mg every 90 minutes to a maximum of 16 mg, or when the patient feels no more withdrawal symptoms. Most patients seem to start with 12mg/3mg, or less, as their daily dose. They are instructed to take the total induction dose as a single dose every day after the initial induction. They are also given a prescription for clonidine 0.1 mg Q4-6 h for the first week.
Only 2 or 3 patients have been unable to use the once daily dosage. Those few admit it is more habit than addiction for which they desire the split dosing.
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