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- Tue Dec 20, 2016 2:54 am
- Forum: Clinical Use of Buprenorphine
- Topic: But Discontinuation Syndrome ??? Studies
- Replies: 7
The difficulty in going from 2 mg to zero, is not a matter of milligrams but a matter of receptor numbers. At 2 mg, buprenorphine still has command of a large number of receptors. Compared to 16 mg, the percentage is small but when compared to 0 mg, it is significant. I think of the normal brain as ...